Vofopitant
Vofopitant (GR 205171) is a potent and selective neurokinin-1 (NK1) receptor antagonist. It is utilized in preclinical research to investigate mechanisms of anxiety, stress, and emesis, with applications in studying PTSD and chemotherapy-induced nausea in both in vitro and in vivo models.
Product Specifications
CAS Number
168266-90-8
Product Name Alternative
Rat NK1 receptor, Vofopitant, Human NK1 receptor, GR205171, GR-205171, GR 205171, Ferret NK1 receptor, Neurokinin receptor, Neurokininreceptor, NK1
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
97.61% (May vary between batches)
Smiles
C (F) (F) (F) C=1N (N=NN1) C2=CC (CN[C@@H]3[C@@H] (NCCC3) C4=CC=CC=C4) =C (OC) C=C2
Molecular Formula
C21H23F3N6O
Molecular Weight
432.44
Storage Conditions
-20°C
Notes
For research use only.
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