Vofopitant dihydrochloride
Vofopitant dihydrochloride (GR 205171A) is a selective, orally active NK1 receptor antagonist with high affinity (pKi 9.5-10.6) . It is used in research to investigate the mechanisms of emesis and has demonstrated anti-vomiting efficacy in preclinical animal models.
Product Specifications
CAS Number
168266-51-1
Product Name Alternative
GR 205171A, NK1, human, NK1, rat, NK1, Neurokininreceptor, Neurokinin receptor, Vofopitant, Vofopitant 2HCl
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
98.99% (May vary between batches)
Solubility
H2O:20 mg/mL (39.58 mM) ; DMSO:20 mg/mL (39.58 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.96 mM)
Smiles
Cl.Cl.COc1ccc (cc1CN[C@H]1CCCN[C@H]1c1ccccc1) -n1nnnc1C (F) (F) F
Molecular Formula
C21H25Cl2F3N6O
Molecular Weight
505.36
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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