SARS-CoV-2 Mpro-IN-21

SARS-CoV-2 Mpro-IN-21 (compound A8) is a potent SARS-CoV-2 and OVID-19 Main Protease MPro inhibitor. SARS-CoV-2 Mpro-IN-21 shows excellent antioxidant activity in DPPH assay with an IC50 of 0.36 mg/mL. SARS-CoV-2 Mpro-IN-21 also exhibits better antibacterial potency against Klebsiella with an IC50 of 1.19 mg/mL[1].

Product Specifications

CAS Number

[3041099-79-7]

UNSPSC

12352005

Target

SARS-CoV

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/sars-cov-2-mpro-in-21.html

Smiles

O=C(N(CC)C(N1CC)=S)/C(C1=O)=C/NCCC2=CC=CC=C2

Molecular Formula

C17H21N3O2S

Molecular Weight

331.43

References & Citations

[1]Sarfraz M, et al. New Pyrimidinone Bearing Aminomethylenes and Schiff Bases as Potent Antioxidant, Antibacterial, SARS-CoV-2, and COVID-19 Main Protease MPro Inhibitors: Design, Synthesis, Bioactivities, and Computational Studies. ACS Omega. 2024 Jun 4;9 (24) :25730-25747.