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WS-383 free base

WS-383 free base is a potent, selective, and reversible small-molecule inhibitor of the DCN1-UBC12 protein-protein interaction, exhibiting an IC50 of 11 nM. This compound is a valuable chemical probe for investigating cullin neddylation pathways in biochemical and cellular studies.

Product Specifications

CAS Number

2247543-65-1

Field of Research

Protein Biochemistry

Smiles

S (C=1N2C (=NC (SCC3=CC=C (Cl) C=C3) =N2) N=C (C) C1) C=4N (CCN (C) C) N=NN4

Molecular Formula

C18H20ClN9S2

Molecular Weight

461.99

Storage Conditions

-20°C

Notes

For research use only.

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