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XRK3F2

XRK3F2 is a small molecule inhibitor targeting the p62-ZZ domain. In vitro, it counteracts myeloma-induced suppression of Runx2, a key osteogenic transcription factor. In vivo, it promotes new bone formation and remodeling even in a tumor-bearing microenvironment, making it a valuable research tool for studying bone biology and oncology.

Product Specifications

CAS Number

2375193-43-2

Product Name Alternative

P62-ZZ, P62-ZZ domain, XRK3F2, XRK-3F2

Field of Research

Cell Biology

Purity

98.75% (May vary between batches)

Solubility

H2O:0.8 mg/mL (1.84 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (9.18 mM) ; DMSO:135 mg/mL (309.71 mM)

Smiles

Cl.OCCNCc1ccc (OCc2ccc (F) cc2) c (OCc2ccc (F) cc2) c1

Molecular Formula

C23H24ClF2NO3

Molecular Weight

435.89

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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