XY101
XY101 is a potent, selective, and orally bioavailable inverse agonist of RORγ, exhibiting an IC50 of 30 nM and a Kd of 380 nM with favorable metabolic stability. This small molecule is a valuable research tool for investigating RORγ's role in immunology and oncology, enabling both in vitro mechanistic studies and in vivo pharmacological research.
Product Specifications
CAS Number
2349368-16-5
Product Name Alternative
RORγ, XY101, XY-101, XY 101
Field of Research
Metabolism Research
Purity
98.81% (May vary between batches)
Solubility
DMSO:225 mg/mL (399.3 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (8.87 mM)
Smiles
CCS (=O) (=O) c1ccc (CC (=O) Nc2ccc (cc2) -c2ccc (cc2F) C (O) (C (F) (F) F) C (F) (F) F) cc1
Molecular Formula
C25H20F7NO4S
Molecular Weight
563.48
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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