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Zatebradine hydrochloride

Zatebradine hydrochloride (UL-FS-49CL) is a selective HCN channel blocker with IC50 values ranging from 1.83 to 2.21 μM against human HCN1-4 subtypes. This inhibitor is utilized in cardiovascular and neurological research to study pacemaker currents in vitro and heart rate regulation in vivo.

Product Specifications

CAS Number

91940-87-3

Product Name Alternative

HCN Channel, HCN channels, HCNChannel, Zatebradine Hydrochloride, UL-FS-49, UL-FS-49CL

Field of Research

Pharmacology & Drug Discovery

Purity

97.00% (May vary between batches)

Solubility

H2O:90 mg/mL (182.54 mM) ; DMSO:90 mg/mL (182.54 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (6.69 mM)

Smiles

Cl.COc1ccc (CCN (C) CCCN2CCc3cc (OC) c (OC) cc3CC2=O) cc1OC

Molecular Formula

C26H37ClN2O5

Molecular Weight

493.04

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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