ZM223
ZM223 is a potent and selective small molecule inhibitor of the NEDD8-activating enzyme (NAE) . It is a valuable research tool for studying neddylation pathways in cancer biology and has demonstrated activity in both cellular and in vivo models of malignancy.
Product Specifications
CAS Number
2031177-48-5
Product Name Alternative
E1 Enzyme, E1Enzyme, E3Enzyme, E2Enzyme, E3 Enzyme, E2 Enzyme, NAE, NEDD8 activating enzyme (NAE), ZM223, ZM-223, ZM 223
Field of Research
Metabolism Research, Protein Biochemistry
Purity
99.67% (May vary between batches)
Solubility
DMSO:80 mg/mL (159.19 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (6.57 mM)
Smiles
N (C (=O) C1=CC=C (C (F) (F) F) C=C1) C2=NC=3C (S2) =CC (NC (CSC4=CC=C (N) C=C4) =O) =CC3
Molecular Formula
C23H17F3N4O2S2
Molecular Weight
502.53
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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