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(3S,4R) -Tofacitinib

(3S,4R) -Tofacitinib is the less active enantiomer of the JAK3 inhibitor Tofacitinib (IC50 = 1 nM) . This compound is used as a comparative control in biochemical and cellular assays to study JAK-STAT signaling pathways in immunological and inflammatory disease research.

Product Specifications

CAS Number

1092578-48-7

Field of Research

Cardiovascular Research, Epigenetics & Chromatin, Pharmacology & Drug Discovery, Signal Transduction, Stem Cell & Developmental Biology

Smiles

C[C@@H]1CCN (C[C@H]1N (C) c1ncnc2[nH]ccc12) C (=O) CC#N

Molecular Formula

C16H20N6O

Molecular Weight

312.37

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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