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(R, S) -Ivosidenib

Ivosidenib is a targeted inhibitor of mutant IDH1 used in research for acute myeloid leukemia (AML) . The (R, S) -enantiomer is the less active form of this compound, serving as a useful control in both in vitro enzymatic assays and in vivo xenograft studies to elucidate the specific effects of the active drug.

Product Specifications

CAS Number

2070009-31-1

Field of Research

Metabolism Research, Neuroscience, Pharmacology & Drug Discovery

Smiles

Fc1cncc (c1) N ([C@@H] (C (=O) NC1CC (F) (F) C1) c1ccccc1Cl) C (=O) [C@@H]1CCC (=O) N1c1cc (ccn1) C#N

Molecular Formula

C28H22ClF3N6O3

Molecular Weight

582.96

Storage Conditions

-20°C

Notes

For research use only.

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