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αvβ1 integrin-IN-1

αvβ1 integrin-IN-1 is a highly potent and selective small molecule inhibitor of αvβ1 integrin, demonstrating an IC50 of 0.63 nM. It serves as a valuable research tool for investigating integrin biology and has shown promising antifibrotic activity in both cellular assays and in vivo models of fibrosis.

Product Specifications

CAS Number

1689540-62-2

Product Name Alternative

αVβ1 integrin, αvβ1 integrin, αvβ1 integrin IN 1, αvβ1 integrinIN1, αvβ1 integrin-IN-1, alphavbeta1 integrin-IN-1, avb1 integrin-IN-1

Field of Research

Signal Transduction

Purity

99.39% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (8.95 mM) ; DMSO:250 mg/mL (447.51 mM)

Smiles

S (=O) (=O) (N1[C@H] (C (N[C@@H] (CC2=CC=C (NC (CCCCNC (=N) N) =O) C=C2) C (O) =O) =O) CCC1) C3=CC=CC=C3

Molecular Formula

C26H34N6O6S

Molecular Weight

558.65

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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