BCX 1470
BCX 1470 is a potent and selective inhibitor of the serine proteases factor D and C1s, with IC50 values of 96 nM and 1.6 nM, respectively. It demonstrates significantly greater potency against these complement system enzymes than against trypsin. This inhibitor is a valuable research tool for studying the classical and alternative complement pathways in vitro.
Product Specifications
CAS Number
217099-43-9
Field of Research
Immunology & Inflammation, Protein Biochemistry
Smiles
C (=N) (N) C=1SC=2C (C1) =CC=C (OC (=O) C3=CC=CS3) C2
Molecular Formula
C14H10N2O2S2
Molecular Weight
302.37
Storage Conditions
-20°C
Notes
For research use only.
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