Desisobutyryl-ciclesonide
Desisobutyryl-ciclesonide (CIC-AP) is the pharmacologically active metabolite of the anti-inflammatory glucocorticoid ciclesonide, acting via the glucocorticoid receptor. It is widely used in research to study glucocorticoid receptor signaling and anti-inflammatory mechanisms in both in vitro cellular assays and in vivo models of respiratory inflammation.
Product Specifications
CAS Number
161115-59-9
Product Name Alternative
Desisobutyryl ciclesonide, Desisobutyrylciclesonide, Desisobutyryl-ciclesonide, CIC-AP, Ciclesonide active principle
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Solubility
DMSO:80 mg/mL (170 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (7.01 mM)
Smiles
C (CO) (=O) [C@]12[C@]3 (C) [C@@] (C[C@]1 (O[C@H] (O2) [C@H]4CCCCC4) [H]) ([C@]5 ([C@] ([C@@H] (O) C3) ([C@]6 (C) C (CC5) =CC (=O) C=C6) [H]) [H]) [H]
Molecular Formula
C28H38O6
Molecular Weight
470.6
Storage Conditions
-20°C
Notes
For research use only.
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