Eribulin

Eribulin (B1939) is a synthetic microtubule dynamics inhibitor that suppresses microtubule polymerization, halting the growth and shrinkage phases essential for cell division. It is widely used in preclinical research for metastatic breast cancer and various solid tumors, with applications in both in vitro cytotoxicity assays and in vivo xenograft models.

Product Specifications

CAS Number

253128-41-5

Product Name Alternative

ER086526, ER-086526, Eribulin, ER 086526, MicrotubuleAssociated, Microtubule Associated, microtubule, B 1939, B-1939, B1939, ADCCytotoxin, ADC Cytotoxin, E7389, E-7389, E 7389

Field of Research

Cell Biology, Pharmacology & Drug Discovery, Signal Transduction

Purity

99.59% (May vary between batches)

Solubility

DMSO:100 mg/mL (137.01 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (6.85 mM)

Smiles

[H][C@@]12CC (=C) [C@] ([H]) (CC[C@@]3 ([H]) C[C@@H] (C) C (=C) [C@@] ([H]) (C[C@]4 ([H]) O[C@H] (C[C@H] (O) CN) [C@H] (OC) [C@@]4 ([H]) CC (=O) C[C@@]4 ([H]) CC[C@]5 ([H]) O[C@@]6 ([H]) [C@@]7 ([H]) O[C@@]8 (C[C@@]7 ([H]) O[C@@]6 ([H]) [C@@] ([H]) (O8) [C@@]5 ([H]) O4) CC1) O3) O2