GLPG2451
GLPG2451 is a potent CFTR enhancer with an EC50 of 11.1 nM for cold-rescued F508del-CFTR. It is a valuable research tool for investigating CFTR function and potential therapeutic strategies for cystic fibrosis in both cellular and animal model systems.
Product Specifications
CAS Number
2055015-61-5
Product Name Alternative
GLPG 2451, GLPG2451, GLPG-2451, Cystic fibrosis transmembrane conductance regulator, CysteineProtease, Cysteine Protease
Field of Research
Pharmacology & Drug Discovery
Purity
99.13% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween-80+45% Saline:3.3 mg/mL (7.87 mM) ; DMSO:200 mg/mL (476.89 mM)
Smiles
S (=O) (=O) (C=1C=C (N) C (C (NC[C@H] (C) O) =O) =NC1) C2=CC=C (OC (F) (F) F) C=C2
Molecular Formula
C16H16F3N3O5S
Molecular Weight
419.38
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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