IRucaparib-AP6
IRucaparib-AP6 is a PROTAC-based, non-trapping PARP1 degrader that eliminates both the enzymatic and scaffolding functions of PARP1. This tool compound is useful for in vitro and in vivo studies investigating PARP1's roles in DNA repair and cancer biology.
Product Specifications
CAS Number
2410557-00-3
Field of Research
Epigenetics & Chromatin, Molecular Biology, Pharmacology & Drug Discovery
Smiles
O=C1NCCC2=C (NC3=CC (F) =CC1=C32) C4=CC=C (C=C4) CN (C) CCOCCOCCOCCOCCOCCOCCNC5=CC=CC=6C (=O) N (C (=O) C56) C7C (=O) NC (=O) CC7
Molecular Formula
C46H55FN6O11
Molecular Weight
886.96
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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