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Maytansinoid DM4

DM4 is a thiol-containing maytansine derivative that serves as a highly potent cytotoxic payload in antibody-drug conjugates (ADCs) . It is extensively used in oncology research, demonstrating potent antitumor activity in both in vitro cytotoxicity assays and in vivo xenograft models for targeted cancer therapy.

Product Specifications

CAS Number

799840-96-3

Smiles

C[C@]12[C@@] (O1) (C (C) (C) [C@@]3 (C[C@] (O) ([C@H] (OC) /C=C/C=C (\C) /CC4=CC (N (C) C (=O) C[C@@H]2OC ([C@@H] (N (C (CCC (C) (C) S) =O) C) C) =O) =C (Cl) C (OC) =C4) NC (=O) O3) [H]) [H]

Molecular Formula

C39H56ClN3O10S

Molecular Weight

794.39

Storage Conditions

-20°C

Notes

For research use only.

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