Maytansinoid DM4
DM4 is a thiol-containing maytansine derivative that serves as a highly potent cytotoxic payload in antibody-drug conjugates (ADCs) . It is extensively used in oncology research, demonstrating potent antitumor activity in both in vitro cytotoxicity assays and in vivo xenograft models for targeted cancer therapy.
Product Specifications
CAS Number
799840-96-3
Smiles
C[C@]12[C@@] (O1) (C (C) (C) [C@@]3 (C[C@] (O) ([C@H] (OC) /C=C/C=C (\C) /CC4=CC (N (C) C (=O) C[C@@H]2OC ([C@@H] (N (C (CCC (C) (C) S) =O) C) C) =O) =C (Cl) C (OC) =C4) NC (=O) O3) [H]) [H]
Molecular Formula
C39H56ClN3O10S
Molecular Weight
794.39
Storage Conditions
-20°C
Notes
For research use only.
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