MS4077
MS4077 is a potent PROTAC degrader of anaplastic lymphoma kinase (ALK), exhibiting a binding affinity (Kd) of 37 nM. It serves as a valuable chemical tool for investigating ALK-driven pathologies, such as certain cancers, in both cellular and animal model studies.
Product Specifications
CAS Number
2230077-10-6
Field of Research
Cardiovascular Research, Pharmacology & Drug Discovery, Signal Transduction
Smiles
O=C1NC (=O) C (N2C (=O) C=3C=CC=C (NCCOCCOCCOCCOCCOCCNC (=O) CN4CCC (C5=CC (OC (C) C) =C (C=C5C) NC6=NC=C (Cl) C (=N6) NC=7C=CC=CC7S (=O) (=O) C (C) C) CC4) C3C2=O) CC1
Molecular Formula
C55H72ClN9O13S
Molecular Weight
1134.73
Storage Conditions
-20°C
Notes
For research use only.
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
H8943 96 Tests
Tripartite motif-containing protein 65 (TRIM65) Mouse ELISA Kit
Sign In for Pricing
View Details 
LV725506 1.0 µg DNA
FPGT-TNNI3K Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)
Sign In for Pricing
View Details