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MS4077

MS4077 is a potent PROTAC degrader of anaplastic lymphoma kinase (ALK), exhibiting a binding affinity (Kd) of 37 nM. It serves as a valuable chemical tool for investigating ALK-driven pathologies, such as certain cancers, in both cellular and animal model studies.

Product Specifications

CAS Number

2230077-10-6

Field of Research

Cardiovascular Research, Pharmacology & Drug Discovery, Signal Transduction

Smiles

O=C1NC (=O) C (N2C (=O) C=3C=CC=C (NCCOCCOCCOCCOCCOCCNC (=O) CN4CCC (C5=CC (OC (C) C) =C (C=C5C) NC6=NC=C (Cl) C (=N6) NC=7C=CC=CC7S (=O) (=O) C (C) C) CC4) C3C2=O) CC1

Molecular Formula

C55H72ClN9O13S

Molecular Weight

1134.73

Storage Conditions

-20°C

Notes

For research use only.

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