OPC-28326
OPC-28326 is a selective α2-adrenergic receptor antagonist acting as a peripheral vasodilator, with Ki values of 2040, 285, and 55 nM for the α2A-, α2B-, and α2C-subtypes, respectively. This compound is a valuable research tool for investigating vascular tone, hemodynamics, and adrenergic signaling in both in vitro and in vivo models.
Product Specifications
CAS Number
167626-17-7
Product Name Alternative
α2C-adrenoceptor, α2A adrenoceptor, α2A-adrenergic receptor, α2B adrenoceptor, α2B-adrenergic receptor, α2C adrenoceptor, OPC28326, OPC-28326, OPC 28326, Adrenergic Receptor, AdrenergicReceptor
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
98.56% (May vary between batches)
Solubility
DMSO:4.22 mg/mL (10.01 mM)
Smiles
C (=O) (C1=CC (C) =C (NC (CC) =O) C (C) =C1) N2CCC (N (CCC3=CC=CC=C3) C) CC2
Molecular Formula
C26H35N3O2
Molecular Weight
421.58
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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