Sulfo-ara-F-NMN
Sulfo-ara-F-NMN is a cell-permeable NMN analog that selectively activates SARM1 while inhibiting CD38 (IC50 ~10 μM) . This activation induces SARM1 conformational changes, leading to cADPR production, NAD+ depletion, and non-apoptotic cell death, making it a valuable tool for studying neurobiology and axon degeneration in vitro.
Product Specifications
CAS Number
1374663-29-2
Field of Research
Immunology & Inflammation
Smiles
F[C@@H]1[C@@H] (O[C@H] (COP (=O) ([O-]) S) [C@H]1O) [N+]=2C=C (C (N) =O) C=CC2
Molecular Formula
C11H14FN2O6PS
Molecular Weight
352.28
Storage Conditions
-20°C
Notes
For research use only.
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