TL13-12
TL13-12 is a potent and selective ALK-PROTAC degrader that effectively inhibits ALK kinase activity with an IC50 of 0.69 nM. This compound is a valuable chemical tool for investigating ALK-driven pathologies, such as certain cancers, in both cellular and animal model research contexts.
Product Specifications
CAS Number
2229037-04-9
Field of Research
Cardiovascular Research, Pharmacology & Drug Discovery, Signal Transduction
Smiles
COc1cc (ccc1Nc1ncc (Cl) c (Nc2ccccc2S (=O) (=O) C (C) C) n1) N1CCN (CCOCCOCCNC (=O) CNc2cccc3C (=O) N (C4CCC (=O) NC4=O) C (=O) c23) CC1
Molecular Formula
C45H53ClN10O10S
Molecular Weight
961.49
Storage Conditions
-20°C
Notes
For research use only.
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