0990CL
0990CL is a specific inhibitor of heterotrimeric Gαi subunits, binding to GDP-bound Gα to disrupt α2AR-mediated cAMP signaling. In cellular models, it partially restores cAMP at low doses, while higher concentrations (e.g., 10μM) can impact cell viability. This tool compound is valuable for in vitro studies investigating GPCR and cAMP pathways in signal transduction research.
Product Specifications
CAS Number
511514-03-7
Product Name Alternative
Heterotrimeric G-protein complex, Gαi subunit, cAMP, 0990CL
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
98.86% (May vary between batches)
Solubility
DMSO:45 mg/mL (131.03 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.82 mM)
Smiles
N (C=1N=C (C2=C (N1) C=CC=C2) C3=CC=CC=C3) C=4NC (C) (C) C=C (C) N4
Molecular Formula
C21H21N5
Molecular Weight
343.42
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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