3α-Aminocholestane
3α-Aminocholestane (5α-Cholestan-3α-amine) is a potent and selective SHIP1 inhibitor with an IC50 of 2.5 μM. This small molecule is a valuable research tool for studying SHIP1's role in immune cell signaling, applicable in both in vitro biochemical assays and in vivo models of immune regulation and related diseases.
Product Specifications
CAS Number
2206-20-4
Product Name Alternative
SHIP1, 5α-Cholestan-3α-amine, 3alpha-Aminocholestane, 3-A-Aminocholestane, 3a-Aminocholestane, 3AC, 3αAminocholestane, 3α-Aminocholestane, 3α Aminocholestane
Field of Research
Metabolism Research
Purity
≥98.0% (May vary between batches)
Solubility
DMSO:<0.1 mg/mL; Ethanol:30 mg/mL (77.38 mM)
Smiles
[H][C@@]1 (CC[C@@]2 ([H]) [C@]3 ([H]) CC[C@@]4 ([H]) C[C@H] (N) CC[C@]4 (C) [C@@]3 ([H]) CC[C@]12C) [C@H] (C) CCCC (C) C
Molecular Formula
C27H49N
Molecular Weight
387.68
Storage Conditions
-20°C
Notes
For research use only.
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