4- (tert-Butyl) -benzhydroxamic Acid
4- (tert-Butyl) -benzhydroxamic Acid is a PqsR antagonist that inhibits quorum sensing in E. coli and P. aeruginosa with IC50 values of 12.5 μM and 23.6 μM, respectively. It also reduces pyocyanin production in P. aeruginosa (IC50 = 87.2 μM), making it a useful tool for studying bacterial virulence mechanisms in vitro.
Product Specifications
CAS Number
62034-73-5
Field of Research
Infectious Disease & Virology, Signal Transduction
Smiles
C (C) (C) (C) C1=CC=C (C (NO) =O) C=C1
Molecular Formula
C11H15NO2
Molecular Weight
193.24
Storage Conditions
-20°C
Notes
For research use only.
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