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4- (tert-Butyl) -benzhydroxamic Acid

4- (tert-Butyl) -benzhydroxamic Acid is a PqsR antagonist that inhibits quorum sensing in E. coli and P. aeruginosa with IC50 values of 12.5 μM and 23.6 μM, respectively. It also reduces pyocyanin production in P. aeruginosa (IC50 = 87.2 μM), making it a useful tool for studying bacterial virulence mechanisms in vitro.

Product Specifications

CAS Number

62034-73-5

Field of Research

Infectious Disease & Virology, Signal Transduction

Smiles

C (C) (C) (C) C1=CC=C (C (NO) =O) C=C1

Molecular Formula

C11H15NO2

Molecular Weight

193.24

Storage Conditions

-20°C

Notes

For research use only.

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