A-935142
A-935142 is a small molecule activator of the hERG (Kv11.1) potassium channel. It modulates channel gating by slowing inactivation and promoting activation, leading to shortened cardiac repolarization. This compound is used in vitro and in vivo to study arrhythmia mechanisms and cardiac electrophysiology.
Product Specifications
CAS Number
1031335-85-9
Product Name Alternative
A 935142, A935142, A-935142, hERG Potassium Channel
Field of Research
Cardiovascular Research, Pharmacology & Drug Discovery, Signal Transduction
Purity
98.97% (May vary between batches)
Solubility
DMSO:5.63 mg/mL (15.98 mM)
Smiles
C (F) (F) (F) C1=CC (=NN1) C2=CC=C (C=C2) [C@H]3CC[C@H] (CC (O) =O) CC3
Molecular Formula
C18H19F3N2O2
Molecular Weight
352.35
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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