Abaperidone
Abaperidone is a potent dual antagonist of the 5-HT2A (IC50 = 6.2 nM) and dopamine D2 (IC50 = 17 nM) receptors. This research compound exhibits atypical antipsychotic potential, as evidenced by its ability to reduce basal hsp70 mRNA expression in rat striatum and prefrontal cortex in vivo studies.
Product Specifications
CAS Number
183849-43-6
Product Name Alternative
Dopamine Receptor, DopamineReceptor, D2 Receptor, D2 receptor, 5HTReceptor, 5HT Receptor, Abaperidone, 5-HT2A Receptor, 5-HT2A
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
94.35% (May vary between batches)
Solubility
DMSO:1.46 mg/mL (3.23 mM)
Smiles
FC=1C=C2C (C (=NO2) C3CCN (CCCOC=4C=C5C (=CC4) C (=O) C (CO) =CO5) CC3) =CC1
Molecular Formula
C25H25FN2O5
Molecular Weight
452.47
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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