ABL127
ABL127 is a potent, selective, and covalent inhibitor of Protein Methylesterase 1 (PME-1), demonstrating low nanomolar IC50 values of 6.4 nM and 4.2 nM in HEK293T and MDA-MB-231 cells, respectively. This small molecule is a valuable chemical probe for investigating PME-1's role in cancer biology and cellular signaling pathways in vitro.
Product Specifications
CAS Number
1073529-41-5
Field of Research
Metabolism Research
Smiles
COC (=O) N1N (C (=O) OC) [C@@] (C2CCCC2) (C1=O) C1=CC=CC=C1
Molecular Formula
C17H20N2O5
Molecular Weight
332.35
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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