Apinocaltamide
Apinocaltamide (ACT-709478) is a brain-penetrant, selective T-type calcium channel blocker with IC50 values of 6.4-18 nM against Cav3.1, Cav3.2, and Cav3.3 subtypes. This compound is a valuable research tool for investigating epilepsy and related neurological disorders in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
1838651-58-3
Product Name Alternative
Cav1.2, Cav3.1, Cav3.2, Cav3.3, ACT 709478, ACT709478, ACT-709478, NBI827104, NBI 827104
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Purity
99.80% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween-80+45% Saline:3.3 mg/mL (7.76 mM) ; DMSO:120 mg/mL (282.08 mM)
Smiles
N#CC1=CN=C (C=C1) CN2N=C (C=C2) NC (=O) CC3=CC=C (C=C3) C4 (CC4) C (F) (F) F
Molecular Formula
C22H18F3N5O
Molecular Weight
425.41
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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