AG-825
AG-825 (Tyrphostin C15) is a selective ErbB2/HER2 inhibitor with an IC50 of 0.35 μM, demonstrating anticancer activity in breast cancer xenograft models. It has also been investigated in neurotoxicity and Alzheimer's disease research, and shown to induce apoptosis in human neutrophils in vitro.
Product Specifications
CAS Number
149092-50-2
Product Name Alternative
Apoptosis, AG 825, AG825, AG-825, ErbB2, EGFR, Tyrphostin AG 825, Tyrphostin AG825, Tyrphostin AG-825
Field of Research
Cardiovascular Research, Cell Biology, Neuroscience, Pharmacology & Drug Discovery, Signal Transduction
Purity
98.43% (May vary between batches)
Solubility
10% DMSO+90% Saline:3.3 mg/mL (8.3 mM) ; DMSO:200 mg/mL (503.18 mM)
Smiles
COc1cc (\C=C (/C#N) C (N) =O) cc (CSc2nc3ccccc3s2) c1O
Molecular Formula
C19H15N3O3S2
Molecular Weight
397.47
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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