AM679
AM679 is a potent and selective FLAP inhibitor, demonstrating sub-nanomolar activity in binding and human leukotriene assays. It exhibits a favorable CYP profile with no time-dependent inhibition and provides strong oral efficacy in rodent models of airway inflammation, making it a valuable tool for researching leukotriene biosynthesis pathways in both in vitro and in vivo settings.
Product Specifications
CAS Number
1206880-66-1
Product Name Alternative
AM679, AM-679, AM 679
Field of Research
Immunology & Inflammation, Metabolism Research
Purity
99.45% (May vary between batches)
Solubility
10% DMSO+90% Corn Oil:3.3 mg/mL (4.76 mM) ; DMSO:≥ 80 mg/mL
Smiles
C (N1C=2C (C (SC (C) (C) C) =C1CC (C (O) =O) (C) C) =CC (OC[C@H]3N (C (C) =O) C=4C (C3) =CC=CC4) =CC2) C5=CC=C (C=C5) C=6N=CC (OC) =CN6
Molecular Formula
C40H44N4O5S
Molecular Weight
692.87
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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