AMG-009
AMG-009 is a potent small molecule dual antagonist targeting both the CRTH2 and DP receptors with high selectivity, exhibiting IC50 values of 3 nM and 12 nM, respectively. It is a valuable research tool for investigating the roles of these prostanoid receptors in allergic inflammation and asthma, applicable in both in vitro binding assays and in vivo disease models.
Product Specifications
CAS Number
1027847-67-1
Product Name Alternative
CRTh2, CRTH2/DP2 Receptor, DP, AMG 009, AMG009, AMG-009, ProstaglandinReceptor, Prostaglandin Receptor
Field of Research
Immunology & Inflammation, Metabolism Research, Pharmacology & Drug Discovery
Purity
97.88% (May vary between batches)
Solubility
DMSO:100 mg/mL (171.98 mM)
Smiles
O=C (O) CC1=CC=C (OC2=CC=C (C=C2NS (=O) (=O) C3=CC=C (Cl) C=C3Cl) C (=O) NCCCC) C (OC) =C1
Molecular Formula
C26H26Cl2N2O7S
Molecular Weight
581.47
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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