Apafant
Apafant (WEB 2086) is a potent and selective platelet-activating factor (PAF) receptor antagonist. It effectively inhibits PAF-induced eosinophil activation and is a valuable tool for investigating allergic diseases, including experimental allergic conjunctivitis, in both in vitro and in vivo models.
Product Specifications
CAS Number
105219-56-5
Product Name Alternative
Apafant, PAFR, WEB 2086, WEB2086, WEB-2086, Platelet-activating factor
Field of Research
Pharmacology & Drug Discovery
Purity
99.56% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween-80+45% Saline:3.3 mg/mL (7.24 mM) ; DMSO:30 mg/mL (65.8 mM)
Smiles
O=C (N1CCOCC1) CCC=2SC3=C (C2) C (=NCC4=NN=C (N43) C) C=5C=CC=CC5Cl
Molecular Formula
C22H22ClN5O2S
Molecular Weight
455.96
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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