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Apafant

Apafant (WEB 2086) is a potent and selective platelet-activating factor (PAF) receptor antagonist. It effectively inhibits PAF-induced eosinophil activation and is a valuable tool for investigating allergic diseases, including experimental allergic conjunctivitis, in both in vitro and in vivo models.

Product Specifications

CAS Number

105219-56-5

Product Name Alternative

Apafant, PAFR, WEB 2086, WEB2086, WEB-2086, Platelet-activating factor

Field of Research

Pharmacology & Drug Discovery

Purity

99.56% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween-80+45% Saline:3.3 mg/mL (7.24 mM) ; DMSO:30 mg/mL (65.8 mM)

Smiles

O=C (N1CCOCC1) CCC=2SC3=C (C2) C (=NCC4=NN=C (N43) C) C=5C=CC=CC5Cl

Molecular Formula

C22H22ClN5O2S

Molecular Weight

455.96

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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