Alrizomadlin
Alrizomadlin (APG-115) is an orally bioavailable MDM2-p53 interaction inhibitor. It demonstrates potent, dose-dependent anti-proliferative activity in TP53 wild-type AML cell lines such as MOLM-13 and induces p53-dependent cell cycle arrest and apoptosis, supporting its investigation in cancer research.
Product Specifications
CAS Number
1818393-16-6
Product Name Alternative
AA 115, AA115, AA-115, APG 115, APG115, APG-115, Alrizomadlin, Mdm2
Field of Research
Cell Biology, Protein Biochemistry
Purity
98.41% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (7.78 mM) ; DMSO:81.67 mg/mL (127.1 mM)
Smiles
CCN1[C@H] ([C@H] (c2cccc (Cl) c2F) [C@]2 (C (=O) Nc3cc (Cl) ccc23) C11CCCCC1) C (=O) NC12CCC (CC1) (CC2) C (O) =O
Molecular Formula
C34H38Cl2FN3O4
Molecular Weight
642.59
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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