AT2 receptor agonist C21
Buloxibutid (C21) is a selective AT2 receptor agonist with high affinity (Ki = 0.4 nM) and significant selectivity over the AT1 receptor. It is a valuable research tool for investigating the renin-angiotensin system in models of cardiovascular and renal disease, fibrosis, and inflammation, both in vitro and in vivo.
Product Specifications
CAS Number
477775-14-7
Product Name Alternative
AT2 receptor agonist C21, AT2, AT2 receptor, AT1, Buloxibutid
Field of Research
Epigenetics & Chromatin; Pharmacology & Drug Discovery, Metabolism Research
Purity
97.68% (May vary between batches)
Solubility
DMSO:22.5 mg/mL (47.31 mM) ;10% DMSO+40% PEG300+5% Tween-80+45% Saline:2 mg/mL (4.21 mM)
Smiles
CCCCOC (=O) NS (=O) (=O) c1sc (CC (C) C) cc1-c1ccc (Cn2ccnc2) cc1
Molecular Formula
C23H29N3O4S2
Molecular Weight
475.62
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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