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Atabecestat

Atabecestat (JNJ-54861911) is a brain-penetrant, orally administered BACE1 inhibitor investigated for preclinical Alzheimer's disease. It has been studied in vitro and in vivo for its ability to reduce amyloid-beta production and has been evaluated in clinical trials targeting early disease intervention.

Product Specifications

CAS Number

1200493-78-2

Product Name Alternative

BACE1, Atabecestat, JNJ 54861911, JNJ54861911, JNJ-54861911, RSC-385896

Field of Research

Neuroscience

Purity

98.49% (May vary between batches)

Solubility

DMSO:200 mg/mL (544.37 mM)

Smiles

C[C@]1 (C=CSC (N) =N1) c1cc (NC (=O) c2ccc (cn2) C#N) ccc1F

Molecular Formula

C18H14FN5OS

Molecular Weight

367.4

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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