Atabecestat
Atabecestat (JNJ-54861911) is a brain-penetrant, orally administered BACE1 inhibitor investigated for preclinical Alzheimer's disease. It has been studied in vitro and in vivo for its ability to reduce amyloid-beta production and has been evaluated in clinical trials targeting early disease intervention.
Product Specifications
CAS Number
1200493-78-2
Product Name Alternative
BACE1, Atabecestat, JNJ 54861911, JNJ54861911, JNJ-54861911, RSC-385896
Field of Research
Neuroscience
Purity
98.49% (May vary between batches)
Solubility
DMSO:200 mg/mL (544.37 mM)
Smiles
C[C@]1 (C=CSC (N) =N1) c1cc (NC (=O) c2ccc (cn2) C#N) ccc1F
Molecular Formula
C18H14FN5OS
Molecular Weight
367.4
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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