Autotaxin-IN-1
Autotaxin-IN-1 is a potent and selective small molecule inhibitor of autotaxin with an IC50 of 2.2 nM. It demonstrates favorable pharmacokinetics and a robust PK/PD relationship, supporting its use in research for osteoarthritis pain and other conditions involving lysophosphatidic acid (LPA) signaling.
Product Specifications
CAS Number
1619971-30-0
Field of Research
Metabolism Research, Signal Transduction
Smiles
C (COCCC1=CN=NN1) (=O) N2CC=3C (C2) =CN=C (NC4CC=5C (C4) =CC=CC5) N3
Molecular Formula
C21H23N7O2
Molecular Weight
405.45
Storage Conditions
-20°C
Notes
For research use only.
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