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Spebrutinib besylate

Spebrutinib besylate (CC-292) is a potent, covalent inhibitor of Bruton's tyrosine kinase (Btk) with an IC50 below 0.5 nM. It is widely used in biochemical and cellular research to investigate Btk signaling in autoimmune disorders and B-cell malignancies, with applications in both in vitro and in vivo experimental models.

Product Specifications

CAS Number

1360053-81-1

Field of Research

Cardiovascular Research, Signal Transduction

Smiles

O=C (C=C) NC1=CC=CC (=C1) NC2=NC (=NC=C2F) NC3=CC=C (OCCOC) C=C3.O=S (=O) (O) C=1C=CC=CC1

Molecular Formula

C28H28FN5O6S

Molecular Weight

581.62

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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