Spebrutinib besylate
Spebrutinib besylate (CC-292) is a potent, covalent inhibitor of Bruton's tyrosine kinase (Btk) with an IC50 below 0.5 nM. It is widely used in biochemical and cellular research to investigate Btk signaling in autoimmune disorders and B-cell malignancies, with applications in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
1360053-81-1
Field of Research
Cardiovascular Research, Signal Transduction
Smiles
O=C (C=C) NC1=CC=CC (=C1) NC2=NC (=NC=C2F) NC3=CC=C (OCCOC) C=C3.O=S (=O) (O) C=1C=CC=CC1
Molecular Formula
C28H28FN5O6S
Molecular Weight
581.62
Storage Conditions
-20°C
Notes
For research use only.
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