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Barasertib

AZD1152 is the pro-drug of Barasertib, a highly selective Aurora B kinase inhibitor with a cell-free assay IC50 of 0.37 nM. It is widely used in cancer research, demonstrating antitumor activity in both in vitro cellular studies and in vivo xenograft models of leukemia and solid tumors.

Product Specifications

CAS Number

722543-31-9

Product Name Alternative

Leukemia, Inhibitor, inhibit, lung, AuroraKinase, Aurora B, Aurora Kinase, AZD 1152, AZD1152, AZD-1152, Barasertib, Apoptosis, cancer, colon, breast

Field of Research

Cell Biology, Epigenetics & Chromatin

Purity

98.10% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.4 mM) ; DMSO:33 mg/mL (56.17 mM)

Smiles

CCN (CCCOc1ccc2c (Nc3cc (CC (=O) Nc4cccc (F) c4) [nH]n3) ncnc2c1) CCOP (O) (O) =O

Molecular Formula

C26H31FN7O6P

Molecular Weight

587.54

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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