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AZD2423

AZD2423 is a potent, selective, and orally bioavailable negative allosteric modulator of the CCR2 receptor, exhibiting an IC50 of 1.2 nM in calcium flux assays. This small molecule is a valuable research tool for investigating CCR2's role in inflammatory and metabolic diseases in both cellular and animal models.

Product Specifications

CAS Number

1229603-37-5

Field of Research

Immunology & Inflammation, Infectious Disease & Virology, Pharmacology & Drug Discovery

Smiles

CC (C) (C) N1CCN[C@H] (C1) C (=O) N1CCN (CC1) C (=O) Nc1ccc (Cl) c (F) c1

Molecular Formula

C20H29ClFN5O2

Molecular Weight

425.93

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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