AZD8797
AZD8797 (KAND567) is a selective, orally bioavailable antagonist of human CX3CR1 and CXCR2. It has shown potential in research models to protect against SARS-CoV-2-related neuronal damage and to attenuate migraine-associated nociceptive sensitization and microglial activation in post-seizure rats.
Product Specifications
CAS Number
911715-90-7
Product Name Alternative
CX3CR1, CXCR2, AZD 8797, AZD8797, AZD-8797, [125I]-CX3CL1-CX3CR1, 125I-IL-8-CXCR2, KAN-0440567, KAND567
Field of Research
Cell Biology, Immunology & Inflammation, Pharmacology & Drug Discovery
Purity
98.73% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (9.91 mM) ; DMSO:100 mg/mL (247.79 mM)
Smiles
CC (C) C[C@H] (CO) Nc1nc (S[C@@H] (C) c2ccccc2) nc2nc (N) sc12
Molecular Formula
C19H25N5OS2
Molecular Weight
403.56
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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