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B022

B022 is a potent and selective NIK inhibitor (Ki = 4.2 nM) used as a chemical probe to study NF-κB signaling. It has demonstrated protective effects against oxidative stress and toxin-induced liver inflammation and injury in preclinical in vivo models, supporting research in hepatology and inflammation.

Product Specifications

CAS Number

1202764-53-1

Product Name Alternative

B022, B-022, B 022, NIK, NF-κB-inducing kinase NIK, NFκB, NF-kB, NFkB

Field of Research

Signal Transduction

Purity

99.55% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (12.57 mM) ; DMSO:200 mg/mL (502.66 mM)

Smiles

CC (O) (C#Cc1ccc2CCN (c2c1) c1nc (N) ncc1Cl) c1nccs1

Molecular Formula

C19H16ClN5OS

Molecular Weight

397.88

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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