B022
B022 is a potent and selective NIK inhibitor (Ki = 4.2 nM) used as a chemical probe to study NF-κB signaling. It has demonstrated protective effects against oxidative stress and toxin-induced liver inflammation and injury in preclinical in vivo models, supporting research in hepatology and inflammation.
Product Specifications
CAS Number
1202764-53-1
Product Name Alternative
B022, B-022, B 022, NIK, NF-κB-inducing kinase NIK, NFκB, NF-kB, NFkB
Field of Research
Signal Transduction
Purity
99.55% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (12.57 mM) ; DMSO:200 mg/mL (502.66 mM)
Smiles
CC (O) (C#Cc1ccc2CCN (c2c1) c1nc (N) ncc1Cl) c1nccs1
Molecular Formula
C19H16ClN5OS
Molecular Weight
397.88
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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