Barbadin
Barbadin is a specific inhibitor of β-arrestin/β2-adaptin interactions, blocking agonist-promoted endocytosis of GPCRs like the β2-adrenergic receptor. It has been used in research on obesity, demonstrating in vivo effects such as potentiating lorcaserin-induced weight loss in animal models.
Product Specifications
CAS Number
356568-70-2
Product Name Alternative
Barbadin, β-arrestin2, β-arrestin, β-arrestin1
Field of Research
Cell Biology, Pharmacology & Drug Discovery
Purity
98.93% (May vary between batches)
Solubility
DMSO:60 mg/mL (179.96 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6 mM)
Smiles
Nn1cnc2scc (-c3ccc (Cc4ccccc4) cc3) c2c1=O
Molecular Formula
C19H15N3OS
Molecular Weight
333.41
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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