BAY 60-6583
BAY 60-6583 is a potent and selective agonist of the adenosine A2B receptor (EC50 = 3 nM), demonstrating cardioprotective effects in myocardial ischemia models. Its species-specific binding affinity (Ki: mouse 750 nM, rabbit 340 nM, dog 330 nM) supports its use in cardiovascular and inflammatory disease research across in vitro and in vivo studies.
Product Specifications
CAS Number
910487-58-0
Product Name Alternative
BAY 60 6583, BAY 606583, BAY 60-6583, Adenosine Receptor, AdenosineReceptor, A1, A2A, A2B, A3
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
97.93% (May vary between batches)
Solubility
DMSO:90 mg/mL (237.19 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (10.54 mM)
Smiles
NC (=O) CSc1nc (N) c (C#N) c (-c2ccc (OCC3CC3) cc2) c1C#N
Molecular Formula
C19H17N5O2S
Molecular Weight
379.44
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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