BETd-260
BETd-260 is a heterobifunctional PROTAC molecule designed to degrade BRD4. It effectively reduces BRD4 protein levels in leukemia cell lines in vitro, making it a useful chemical probe for studying BET protein function and targeted protein degradation in oncology research.
Product Specifications
CAS Number
2093388-62-4
Product Name Alternative
Epigenetic Reader Domain, EpigeneticReaderDomain, BRD4, BETd-260, PROTAC, ZBC 260, ZBC260, ZBC-260
Field of Research
Cell Biology, Epigenetics & Chromatin, Pharmacology & Drug Discovery
Purity
96.76% (May vary between batches)
Solubility
DMSO:22.5 mg/mL (28.16 mM) ; H2O:Insoluble;10% DMSO+40% PEG300+5% Tween-80+45% Saline:0.5 mg/mL (0.63 mM)
Smiles
N (C1=C2C=3C (NC2=NC (C (NCCCCCC4=C5C (C (=O) N (C5) C6C (=O) NC (=O) CC6) =CC=C4) =O) =N1) =CC (=C (OC) C3) C=7C (C) =NOC7C) C=8N (CC) N=C (C8) C9CC9
Molecular Formula
C43H46N10O6
Molecular Weight
798.89
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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